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1

Synthesis, Binding, and Modeling Studies of New Cytisine Derivatives, as Ligands for Neuronal Nicotinic Acetylcholine Receptor Subtypes

Tasso, Bruno, Canu Boido, Caterina, Terranova, Emanuela, Gotti, Cecilia, Riganti, Loredana, Clementi, Francesco, Artali, Roberto, Bombieri, Gabriella, Meneghetti, Fiorella, Sparatore, Fabio

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 4.42 MB

english, 2009

2

The Influence of the Nitrogen Substitution in Three Cytisine Derivatives as Ligands for the Neuronal nAChRs: A Structural and Theoretical Study

Gabriella Bombieri, Fiorella Meneghetti, Roberto Artali, Bruno Tasso, Caterina Canu Boido, Fabio Sparatore

Journal:

Chemistry & Biodiversity

Year:

2008

Language:

english

File:

PDF, 440 KB

english, 2008

3

Organometallic compounds in oncology: implications of novel organotins as antitumor agents

Angela Alama, Bruno Tasso, Federica Novelli, Fabio Sparatore

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 599 KB

english, 2009

4

Erratum to “2-Phenyl-3-(quinolizidin-1-yl)-5-substituted indoles as platelet anti-aggregating agents” [Il Farmaco 59 (2004) 101–109]

Marcella Ercoli, Lorenzo Mina, Caterina Canu Boido, Vito Boido, Fabio Sparatore, Ugo Armani, Antonietta Piana

Journal:

Year:

2004

Language:

english

File:

PDF, 108 KB

english, 2004

5

Anti-inflammatory and gastrointestinal effects of a novel diclofenac derivative

Ling Li, Giuseppe Rossoni, Anna Sparatore, Lin Chiou Lee, Piero Del Soldato, Philip Keith Moore

Journal:

Free Radical Biology and Medicine

Year:

2007

Language:

english

File:

PDF, 716 KB

english, 2007

6

Therapeutic potential of new hydrogen sulfide-releasing hybrids

Sparatore, Anna, Santus, Giancarlo, Giustarini, Daniela, Rossi, Ranieri, Del Soldato, Piero

Journal:

Expert Review of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 599 KB

english, 2011

7

Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline

Manolo Casagrande, Anna Barteselli, Nicoletta Basilico, Silvia Parapini, Donatella Taramelli, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1014 KB

english, 2012

8

Role of neuronal nicotinic acetylcholine receptors (nAChRs) on learning and memory in zebrafish

Braida, Daniela, Ponzoni, Luisa, Martucci, Roberta, Sparatore, Fabio, Gotti, Cecilia, Sala, Mariaelvina

Journal:

Psychopharmacology

Year:

2014

Language:

english

File:

PDF, 654 KB

english, 2014

9

α1- and α2-Adrenoreceptor Antagonist Profiles of 1- and 2-[ω-(4-Arylpiperazin-1-yl)alkyl]-1,2,3-benzotriazoles

Alessandro Boido, Roberta Budriesi, Caterina Canu Boido, Pierfranco Ioan, Emanuela Terranova, Alberto Chiarini, Fabio Sparatore

Journal:

Chemistry & Biodiversity

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

10

[4-(2H-1,2,3-Benzotriazol-2-yl)phenoxy]alkanoic Acids as Agonists of Peroxisome Proliferator-Activated Receptors (PPARs)

Anna Sparatore, Cristina Godio, Elena Perrino, Sergio Romeo, Bart Staels, Jean-Charles Fruchart, Maurizio Crestani

Journal:

Chemistry & Biodiversity

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

11

Quinolizidinyl-benzimidazoles as Platelet-Antiaggregating Agents

Iana Vazzana, Emanuela Terranova, Bruno Tasso, Michele Tonelli, Antonietta Piana, Stefanella Gastaldi, Fabio Sparatore

Journal:

Chemistry & Biodiversity

Year:

2008

Language:

english

File:

PDF, 245 KB

english, 2008

12

Antiviral Activity of Benzimidazole Derivatives. I. Antiviral Activity of 1-Substituted-2-[(Benzotriazol-1/2-yl)methyl]benzimidazoles

Michele Tonelli, Giuseppe Paglietti, Vito Boido, Fabio Sparatore, Fabio Marongiu, Esther Marongiu, Paolo La Colla, Roberta Loddo

Journal:

Chemistry & Biodiversity

Year:

2008

Language:

english

File:

PDF, 247 KB

english, 2008

13

ChemInform Abstract: Synthesis and Preliminary Pharmacological Evaluation of 3-(2-(1- Arylpiperazin-4-yl)ethyl)-3,4-dihydro-3-methyl-6-R-1,2,4- benzotriazines.

F. NOVELLI, F. SPARATORE

Journal:

Year:

1997

File:

PDF, 29 KB

1997

14

ChemInform Abstract: Preparation and Pharmacological Activities of Spiro(3,4-dihydro-6/7-R- 1,2,4-benzotriazine-3,4′-(1′-substituted)piperidines).

F. NOVELLI, F. SPARATORE

Journal:

Year:

1997

File:

PDF, 29 KB

1997

15

ChemInform Abstract: 7-(N-Substituted)amino-2,3-polymethylene Benzofuran Derivatives with Tracheal Relaxant Activity.

I. VAZZANA, F. SPARATORE

Journal:

Year:

1997

File:

PDF, 32 KB

1997

16

ChemInform Abstract: New Benzamide-Derived 5-HT3 Receptor Antagonists which Prevent the Effects of Ethanol on Extracellular Dopamine, and Fail to Reduce Voluntary Alcohol Intake in Rats

G. IUSCO, V. BOIDO, F. SPARATORE, G. COLOMBO, P. L. SABA, Z. ROSSETTI, A. VACCARI

Journal:

Year:

1997

File:

PDF, 29 KB

1997

17

ChemInform Abstract: Synthesis and Biological Investigations of 2-(Tetrahydropyran-2′-yl) and 2-(Tetrahydrofuran-2′-yl)benzimidazoles.

F. NOVELLI, B. TASSO, F. SPARATORE, A. SPARATORE

Journal:

Year:

1998

File:

PDF, 37 KB

1998

18

ChemInform Abstract: Synthesis and Biological Investigations of 1-(Tetrahydropyran-2′-yl)- and 1-(Tetrahydrofuran-2′-yl)benzimidazoles and 1/2-(Tetrahydropyran-2′-yl)- and 1/2-(Tetrahydrofuran-2′-yl)benzotriazoles.

A. SPARATORE, F. NOVELLI, F. SPARATORE

Journal:

Year:

1998

File:

PDF, 28 KB

1998

19

ChemInform Abstract: Synthesis and Preliminary Pharmacological Investigation of Some 2-[4-(Dialkylaminoalkoxy)phenyl]benzotriazoles and Their N-Oxides.

A. SPARATORE, F. SPARATORE

Journal:

Year:

1998

File:

PDF, 36 KB

1998

20

ChemInform Abstract: Formation of Basic Compounds During the Indole Cyclization of Ketone Phenylhydrazones.

C. CANU BOIDO, V. BOIDO, F. NOVELLI, F. SPARATORE

Journal:

Year:

1999

File:

PDF, 29 KB

1999

21

ChemInform Abstract: Gold(I) Complexes as Antimicrobial Agents

Federica Novelli, Marco Recine, Fabio Sparatore, Claudia Juliano

Journal:

Year:

1999

File:

PDF, 24 KB

1999

22

ChemInform Abstract: Triorganotin Compounds as Antimicrobial Agents.

Federica Novelli, Marco Recine, Fabio Sparatore, Claudia Juliano

Journal:

Year:

1999

File:

PDF, 26 KB

1999

23

ChemInform Abstract: Quinolizidinyl Derivatives of 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxylic Acid and 1-Homolupinanoyl Benzimidazolones as Ligands for 5-HT3 and 5-HT4 Receptors.

Anna Sparatore, Alfredo Cagnotto, Fabio Sparatore

Journal:

Year:

1999

File:

PDF, 33 KB

1999

24

ChemInform Abstract: Synthesis and Preliminary Pharmacological Evaluation of Some Cytisine Derivatives.

Caterina Canu Boido, Fabio Sparatore

Journal:

Year:

1999

File:

PDF, 25 KB

1999

25

ChemInform Abstract: Quinolizidinyl Derivatives of 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one as Ligands for Muscarinic Receptors.

Federica Novelli, Anna Sparatore, Bruno Tasso, Fabio Sparatore

Journal:

Year:

2000

File:

PDF, 29 KB

2000

26

Spiro[1,2,4-benzotriazine-3(4H),4′-(1-substituted)piperidines] and Related Compounds as Ligands for Sigma Receptors.

Federica Novelli, Fabio Sparatore

Journal:

Year:

2003

File:

PDF, 83 KB

2003

27

Antiinflammatory and Antinociceptive Activities of Some Benzotriazolylalkanoic Acids.

Alessandro Boido, Iana Vazzana, Francesca Mattioli, Fabio Sparatore

Journal:

Year:

2003

File:

PDF, 190 KB

2003

28

N-Homolupinanoyl and N-(ω-Lupinylthio)alkanoyl Derivatives of Some Tricyclic Systems as Ligands for Muscarinic M1 and M2 Receptor Subtypes.

Bruno Tasso, Anna Sparatore, Fabio Sparatore

Journal:

Year:

2004

File:

PDF, 69 KB

2004

29

2-Phenyl-3-(quinolizidin-1-yl)-5-substituted Indoles as Platelet Antiaggregating Agents.

Marcella Ercoli, Lorenzo Mina, Caterina Canu Boido, Vito Boido, Fabio Sparatore, Ugo Armani, Antonietta Piana

Journal:

Year:

2004

File:

PDF, 80 KB

2004

30

Atovaquone-Statine “Double-Drugs” with High Antiplasmodial Activity

Sergio Romeo, Silvia Parapini, Mario Dell'Agli, Nadia Vaiana, Pietro Magrone, Germana Galli, Anna Sparatore, Donatella Taramelli, Enrica Bosisio

Journal:

Year:

2008

Language:

english

File:

PDF, 185 KB

english, 2008

31

Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation

Moonhee Lee, Anna Sparatore, Piero Del Soldato, Edith Mcgeer, Patrick L. McGeer

Journal:

Year:

2010

Language:

english

File:

PDF, 696 KB

english, 2010

32

1-(Arylalkyl)quinolizidine Derivatives and Thio-Isosteric Analogues as Ligands for Sigma Receptors

Anna Sparatore, Federica Novelli, Fabio Sparatore

Journal:

Helvetica Chimica Acta

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

33

Epimerization of Lupinine to Epilupinine and vice versa. Reexamination of the Structures of Lupinal and Epilupinal

Anna Sparatore, Bruno Tasso, Vito Boido, Fabio Sparatore

Journal:

Helvetica Chimica Acta

Year:

2005

Language:

english

File:

PDF, 82 KB

english, 2005

34

Formation of basic compounds during the indole cyclization of ketone phenylhydrazones

Caterina Canu Boido, Vito Boido, Federica Novelli, Fabio Sparatore

Journal:

Journal of Heterocyclic Chemistry

Year:

1998

File:

PDF, 444 KB

1998

35

Field desorption mass spectrometry, fast atom bombardment mass spectrometry and fast atom bombardment tandem mass spectrometry of echinacoside, the main caffeoyl-glycoside from Echinacea angustifolia roots (Asteraceae)

Roberto Maffei Facino, Anna Sparatore, Marina Carini, Bruno Gioia, Emanuele Arlandini, Luigi Franzoi

Journal:

Journal of Mass Spectrometry

Year:

1991

Language:

english

File:

PDF, 344 KB

english, 1991

36

A suggested structure for delsoline

F. Sparatore, R. Greenhalgh, Léo Marion

Journal:

Year:

1958

Language:

english

File:

PDF, 976 KB

english, 1958

37

4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity

Anna Sparatore, Nicoletta Basilico, Silvia Parapini, Sergio Romeo, Federica Novelli, Fabio Sparatore, Donatella Taramelli

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 639 KB

english, 2005

38

Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline

Anna Sparatore, Nicoletta Basilico, Manolo Casagrande, Silvia Parapini, Donatella Taramelli, Reto Brun, Sergio Wittlin, Fabio Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 166 KB

english, 2008

39

Novel amodiaquine congeners as potent antimalarial agents

Manolo Casagrande, Nicoletta Basilico, Silvia Parapini, Sergio Romeo, Donatella Taramelli, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 265 KB

english, 2008

40

Antimicrobial and cytotoxic arylazoenamines. Part III: Antiviral activity of selected classes of arylazoenamines

Michele Tonelli, Vito Boido, Caterina Canu, Anna Sparatore, Fabio Sparatore, Maria Silvia Paneni, Maurizio Fermeglia, Sabrina Pricl, Paolo La Colla, Laura Casula, Cristina Ibba, David Collu, Roberta L

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 726 KB

english, 2008

41

Synthesis, antimalarial activity, and cellular toxicity of new arylpyrrolylaminoquinolines

Manolo Casagrande, Nicoletta Basilico, Chiara Rusconi, Donatella Taramelli, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 418 KB

english, 2010

42

Plasmepsin II inhibition and antiplasmodial activity of Primaquine–Statine `double-drugs'

Sergio Romeo, Mario Dell'Agli, Silvia Parapini, Luca Rizzi, Germana Galli, Monica Mondani, Anna Sparatore, Donatella Taramelli, Enrica Bosisio

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 254 KB

english, 2004

43

New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity

Elena Perrino, Graziella Cappelletti, Valerio Tazzari, Erminio Giavini, Piero Del Soldato, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 162 KB

english, 2008

44

New prostaglandin derivative for glaucoma treatment

Elena Perrino, Caterina Uliva, Cecilia Lanzi, Piero Del Soldato, Emanuela Masini, Anna Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 248 KB

english, 2009

45

Formation of apparent para-benzidine rearrangement products during indole syntheses

F. Sparatore, V. Boido, G. Pirisino

Journal:

Tetrahedron Letters

Year:

1974

Language:

english

File:

PDF, 121 KB

english, 1974

46

Quinolizidinyl derivatives of 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one as ligands for muscarinic receptors

Federica Novelli, Anna Sparatore, Bruno Tasso, Fabio Sparatore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 229 KB

english, 1999

47

ACS6, a Hydrogen sulfide-donating derivative of sildenafil, inhibits homocysteine-induced apoptosis by preservation of mitochondrial function

Xiao-Qing Tang, Rong-Qian Chen, Yan-Kai Ren, Del Piero Soldato, Anna Sparatore, Yuan-Yuan Zhuang, Hen-Rong Fang, Chun-Yan Wang

Journal:

Medical Gas Research

Year:

2011

Language:

english

File:

PDF, 677 KB

english, 2011

48

In vitro cytotoxic activity of tri-n-butyltin(IV)lupinylsulfide hydrogen fumarate (IST-FS 35) and preliminary antitumor activity in vivo

Angela Alama, Maurizio Viale, Michele Cilli, Cristina Bruzzo, Federica Novelli, Bruno Tasso, Fabio Sparatore

Journal:

Investigational New Drugs

Year:

2009

Language:

english

File:

PDF, 165 KB

english, 2009

49

HMGB1 as an autocrine stimulus in human T98G glioblastoma cells: role in cell growth and migration

Rosaria Bassi, Paola Giussani, Viviana Anelli, Thomas Colleoni, Marco Pedrazzi, Mauro Patrone, Paola Viani, Bianca Sparatore, Edon Melloni, Laura Riboni

Journal:

Journal of Neuro-Oncology

Year:

2008

Language:

english

File:

PDF, 475 KB

english, 2008

50

Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity

Valentina Villa, Michele Tonelli, Stefano Thellung, Alessandro Corsaro, Bruno Tasso, Federica Novelli, Caterina Canu, Albiana Pino, Katia Chiovitti, Domenico Paludi, Claudio Russo, Anna Sparatore, Ant

Journal:

Neurotoxicity Research

Year:

2011

Language:

english

File:

PDF, 680 KB

english, 2011